Class: Pathophysiology

URI: dppkb:Pathophysiology

classDiagram class Pathophysiology click Pathophysiology href "../Pathophysiology" Pathophysiology : assays Pathophysiology --> "*" AssayTerm : assays click AssayTerm href "../AssayTerm" Pathophysiology : biological_processes Pathophysiology --> "*" BiologicalProcessTerm : biological_processes click BiologicalProcessTerm href "../BiologicalProcessTerm" Pathophysiology : cell_types Pathophysiology --> "*" CellTypeTerm : cell_types click CellTypeTerm href "../CellTypeTerm" Pathophysiology : cellular_components Pathophysiology --> "*" CellularComponentTerm : cellular_components click CellularComponentTerm href "../CellularComponentTerm" Pathophysiology : chemical_entities Pathophysiology --> "*" ChemicalEntityTerm : chemical_entities click ChemicalEntityTerm href "../ChemicalEntityTerm" Pathophysiology : consequence Pathophysiology : description Pathophysiology : downstream Pathophysiology : evidence Pathophysiology --> "*" EvidenceItem : evidence click EvidenceItem href "../EvidenceItem" Pathophysiology : examples Pathophysiology : gene Pathophysiology --> "0..1" GeneTerm : gene click GeneTerm href "../GeneTerm" Pathophysiology : genes Pathophysiology --> "*" GeneTerm : genes click GeneTerm href "../GeneTerm" Pathophysiology : locations Pathophysiology --> "*" AnatomicalEntityTerm : locations click AnatomicalEntityTerm href "../AnatomicalEntityTerm" Pathophysiology : mechanisms Pathophysiology : name Pathophysiology : notes Pathophysiology : pathways Pathophysiology --> "*" BiologicalProcessTerm : pathways click BiologicalProcessTerm href "../BiologicalProcessTerm" Pathophysiology : role Pathophysiology : subtypes Pathophysiology : synonyms Pathophysiology : triggers Pathophysiology --> "*" TriggerTerm : triggers click TriggerTerm href "../TriggerTerm"

Slots

Name	Cardinality and Range	Inheritance
name	1 String	direct
description	0..1 String	direct
cell_types	* CellTypeTerm	direct
evidence	* EvidenceItem	direct
biological_processes	* BiologicalProcessTerm	direct
locations	* AnatomicalEntityTerm	direct
examples	* String	direct
role	0..1 String	direct
synonyms	* String	direct
consequence	0..1 String	direct
gene	0..1 GeneTerm	direct
pathways	* BiologicalProcessTerm	direct
downstream	* String	direct
genes	* GeneTerm	direct
subtypes	* String	direct
cellular_components	* CellularComponentTerm	direct
chemical_entities	* ChemicalEntityTerm	direct
triggers	* TriggerTerm	direct
assays	* AssayTerm	direct
mechanisms	* String	direct
notes	0..1 String	direct

Usages

used by	used in	type	used
Disease	pathophysiology	range	Pathophysiology

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/dppkb

Mappings

Mapping Type	Mapped Value
self	dppkb:Pathophysiology
native	dppkb:Pathophysiology

LinkML Source

Direct

name: Pathophysiology
from_schema: https://w3id.org/dppkb
slots:
- name
- description
- cell_types
- evidence
- biological_processes
- locations
- examples
- role
- synonyms
- consequence
- gene
- pathways
- downstream
- genes
- subtypes
- cellular_components
- chemical_entities
- triggers
- assays
- mechanisms
- notes

Induced

name: Pathophysiology
from_schema: https://w3id.org/dppkb
attributes:
  name:
    name: name
    examples:
    - value: Adolescent Nephronophthisis
    from_schema: https://w3id.org/dppkb
    rank: 1000
    identifier: true
    alias: name
    owner: Pathophysiology
    domain_of:
    - Subtype
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - Genetic
    - Environmental
    - Disease
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Diagnosis
    - Inheritance
    - Variant
    - Mechanism
    - ModelingConsideration
    range: string
    required: true
  description:
    name: description
    from_schema: https://w3id.org/dppkb
    rank: 1000
    alias: description
    owner: Pathophysiology
    domain_of:
    - Subtype
    - EpidemiologyInfo
    - Pathophysiology
    - Environmental
    - Disease
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Assay
    - Inheritance
    - Variant
    - Mechanism
    - ModelingConsideration
    range: string
  cell_types:
    name: cell_types
    examples:
    - value: '[''Macrophage'', ''T Cell'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: cell_types
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    - Biochemical
    range: CellTypeTerm
  evidence:
    name: evidence
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: evidence
    owner: Pathophysiology
    domain_of:
    - Subtype
    - Prevalence
    - ProgressionInfo
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - Genetic
    - Environmental
    - AnimalModel
    - Treatment
    - InfectiousAgent
    - Transmission
    - Diagnosis
    - Inheritance
    - ModelingConsideration
    range: EvidenceItem
    inlined: true
    inlined_as_list: true
  biological_processes:
    name: biological_processes
    examples:
    - value: '[''TNF-alpha Production'', ''IL-1beta Production'', ''IL-6 Production'',
        ''IL-8 Production'', ''IFN-gamma Production'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: biological_processes
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: BiologicalProcessTerm
  locations:
    name: locations
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: locations
    owner: Pathophysiology
    domain_of:
    - Subtype
    - Pathophysiology
    range: AnatomicalEntityTerm
  examples:
    name: examples
    examples:
    - value: '[''Kaposi Sarcoma'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: examples
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    - Environmental
    range: string
  role:
    name: role
    examples:
    - value: Primary
    from_schema: https://w3id.org/dppkb
    rank: 1000
    alias: role
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    - Treatment
    range: string
  synonyms:
    name: synonyms
    examples:
    - value: '[''CYFRA 21-1'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: synonyms
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    - Biochemical
    - Environmental
    - Disease
    range: string
  consequence:
    name: consequence
    examples:
    - value: Leads to abnormal sexual development and bone maturation.
    from_schema: https://w3id.org/dppkb
    rank: 1000
    alias: consequence
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: string
  gene:
    name: gene
    examples:
    - value: MEFV
    from_schema: https://w3id.org/dppkb
    rank: 1000
    alias: gene
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: GeneTerm
  pathways:
    name: pathways
    examples:
    - value: '[''Wnt Pathway'', ''Hedgehog Pathway'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: pathways
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: BiologicalProcessTerm
  downstream:
    name: downstream
    examples:
    - value: '[''Tissue Damage'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: downstream
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: string
  genes:
    name: genes
    examples:
    - value: '[''HLA-DQ2'', ''HLA-DQ8'', ''INS'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: genes
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    - AnimalModel
    range: GeneTerm
  subtypes:
    name: subtypes
    examples:
    - value: '[''DENV-1'', ''DENV-2'', ''DENV-3'', ''DENV-4'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: subtypes
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: string
  cellular_components:
    name: cellular_components
    examples:
    - value: '[''Peroxisome'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: cellular_components
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: CellularComponentTerm
  chemical_entities:
    name: chemical_entities
    examples:
    - value: '[''Plasmalogen'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: chemical_entities
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: ChemicalEntityTerm
  triggers:
    name: triggers
    examples:
    - value: '[''Viral Infections'', ''Early Dietary Factors'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: triggers
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: TriggerTerm
  assays:
    name: assays
    examples:
    - value: '[''Elevated Blood Glucose'', ''Elevated Hemoglobin A1c (HbA1c)'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: assays
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    - Biochemical
    range: AssayTerm
  mechanisms:
    name: mechanisms
    examples:
    - value: '[''Thrombocytopenia'', ''Platelet Dysfunction'', ''Disseminated Intravascular
        Coagulation (DIC)'']'
    from_schema: https://w3id.org/dppkb
    rank: 1000
    multivalued: true
    alias: mechanisms
    owner: Pathophysiology
    domain_of:
    - Pathophysiology
    range: string
  notes:
    name: notes
    examples:
    - value: Contagious stage where symptoms appear and the bacteria can be spread
        to others.
    from_schema: https://w3id.org/dppkb
    rank: 1000
    alias: notes
    owner: Pathophysiology
    domain_of:
    - Prevalence
    - ProgressionInfo
    - EpidemiologyInfo
    - Pathophysiology
    - Phenotype
    - Biochemical
    - Genetic
    - Environmental
    - Disease
    - Treatment
    - Transmission
    - Diagnosis
    range: string