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Class: CellularSystem

Cell-based model systems that use living cells to model biological processes. Includes 2D cultures, 3D systems, and co-cultures. Conforms to MIACA (Minimal Information About a Cellular Assay) standards.

* __NOTE__: this is an abstract class and should not be instantiated directly URI: [namo:CellularSystem](https://w3id.org/monarch-initiative/namo/CellularSystem)
classDiagram class CellularSystem click CellularSystem href "../CellularSystem/" NAMModel <|-- CellularSystem click NAMModel href "../NAMModel/" CellularSystem <|-- TwoDCellCulture click TwoDCellCulture href "../TwoDCellCulture/" CellularSystem <|-- ThreeDCellCulture click ThreeDCellCulture href "../ThreeDCellCulture/" CellularSystem <|-- CoCulture click CoCulture href "../CoCulture/" CellularSystem : biological_organization_level CellularSystem --> "0..1" BiologicalOrganizationLevelEnum : biological_organization_level click BiologicalOrganizationLevelEnum href "../BiologicalOrganizationLevelEnum/" CellularSystem : cell_source CellularSystem : cell_types CellularSystem --> "*" Cell : cell_types click Cell href "../Cell/" CellularSystem : complexity_level CellularSystem --> "0..1" ComplexityLevelEnum : complexity_level click ComplexityLevelEnum href "../ComplexityLevelEnum/" CellularSystem : culture_conditions CellularSystem : description CellularSystem : id CellularSystem : models CellularSystem --> "*" ModelsRelationship : models click ModelsRelationship href "../ModelsRelationship/" CellularSystem : name CellularSystem : references CellularSystem --> "*" Reference : references click Reference href "../Reference/" CellularSystem : spatial_context CellularSystem : type
## Inheritance * [NamedThing](NamedThing.md) * [ModelSystem](ModelSystem.md) * [NAMModel](NAMModel.md) * **CellularSystem** * [TwoDCellCulture](TwoDCellCulture.md) * [ThreeDCellCulture](ThreeDCellCulture.md) * [CoCulture](CoCulture.md) ## Slots | Name | Cardinality and Range | Description | Inheritance | | --- | --- | --- | --- | | [cell_types](cell_types.md) | *
[Cell](Cell.md) | Cell types present in the cellular system | direct | | [cell_source](cell_source.md) | 0..1
[String](String.md) | Source of cells (e | direct | | [culture_conditions](culture_conditions.md) | 0..1
[String](String.md) | Standard culture conditions and media used | direct | | [biological_organization_level](biological_organization_level.md) | 0..1
[BiologicalOrganizationLevelEnum](BiologicalOrganizationLevelEnum.md) | The level of biological organization represented by the model | [NAMModel](NAMModel.md) | | [spatial_context](spatial_context.md) | 0..1
[String](String.md) | Description of spatial organization and context captured by the model | [NAMModel](NAMModel.md) | | [complexity_level](complexity_level.md) | 0..1
[ComplexityLevelEnum](ComplexityLevelEnum.md) | Level of biological complexity represented (subcellular, cellular, tissue, or... | [NAMModel](NAMModel.md) | | [references](references.md) | *
[Reference](Reference.md) | Literature references that describe, validate, or support this model | [NAMModel](NAMModel.md) | | [models](models.md) | *
[ModelsRelationship](ModelsRelationship.md) | | [ModelSystem](ModelSystem.md) | | [id](id.md) | 1
[Uriorcurie](Uriorcurie.md) | A unique identifier for a thing | [NamedThing](NamedThing.md) | | [name](name.md) | 0..1
[String](String.md) | A human-readable name for a thing | [NamedThing](NamedThing.md) | | [description](description.md) | 0..1
[String](String.md) | A human-readable description for a thing | [NamedThing](NamedThing.md) | | [type](type.md) | 0..1
[String](String.md) | | [NamedThing](NamedThing.md) | ## See Also * [https://doi.org/10.5966/sctm.2015-0393](https://doi.org/10.5966/sctm.2015-0393) ## Identifier and Mapping Information ### Schema Source * from schema: https://w3id.org/monarch-initiative/namo ## Mappings | Mapping Type | Mapped Value | | --- | --- | | self | namo:CellularSystem | | native | namo:CellularSystem | | exact | MIACA:cellular_assay | ## LinkML Source ### Direct 
name: CellularSystem
description: Cell-based model systems that use living cells to model biological processes.
  Includes 2D cultures, 3D systems, and co-cultures. Conforms to MIACA (Minimal Information
  About a Cellular Assay) standards.
from_schema: https://w3id.org/monarch-initiative/namo
see_also:
- https://doi.org/10.5966/sctm.2015-0393
exact_mappings:
- MIACA:cellular_assay
is_a: NAMModel
abstract: true
attributes:
  cell_types:
    name: cell_types
    description: Cell types present in the cellular system
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - CellularSystem
    - OrganOnChip
    range: Cell
    bindings:
    - range: CellTypeEnum
      obligation_level: REQUIRED
      binds_value_of: id
    multivalued: true
    inlined_as_list: true
  cell_source:
    name: cell_source
    description: Source of cells (e.g., primary, iPSC-derived, immortalized cell lines)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - CellularSystem
    - OrganOnChip
  culture_conditions:
    name: culture_conditions
    description: Standard culture conditions and media used
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - CellularSystem
### Induced 
name: CellularSystem
description: Cell-based model systems that use living cells to model biological processes.
  Includes 2D cultures, 3D systems, and co-cultures. Conforms to MIACA (Minimal Information
  About a Cellular Assay) standards.
from_schema: https://w3id.org/monarch-initiative/namo
see_also:
- https://doi.org/10.5966/sctm.2015-0393
exact_mappings:
- MIACA:cellular_assay
is_a: NAMModel
abstract: true
attributes:
  cell_types:
    name: cell_types
    description: Cell types present in the cellular system
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - CellularSystem
    - OrganOnChip
    range: Cell
    bindings:
    - range: CellTypeEnum
      obligation_level: REQUIRED
      binds_value_of: id
    multivalued: true
    inlined: true
    inlined_as_list: true
  cell_source:
    name: cell_source
    description: Source of cells (e.g., primary, iPSC-derived, immortalized cell lines)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - CellularSystem
    - OrganOnChip
    range: string
  culture_conditions:
    name: culture_conditions
    description: Standard culture conditions and media used
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - CellularSystem
    range: string
  biological_organization_level:
    name: biological_organization_level
    description: The level of biological organization represented by the model
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - NAMModel
    range: BiologicalOrganizationLevelEnum
  spatial_context:
    name: spatial_context
    description: Description of spatial organization and context captured by the model
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - NAMModel
    range: string
  complexity_level:
    name: complexity_level
    description: Level of biological complexity represented (subcellular, cellular,
      tissue, organ, system)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - NAMModel
    range: ComplexityLevelEnum
  references:
    name: references
    description: Literature references that describe, validate, or support this model
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - NAMModel
    range: Reference
    multivalued: true
    inlined: true
    inlined_as_list: true
  models:
    name: models
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: CellularSystem
    domain_of:
    - ModelSystem
    range: ModelsRelationship
    multivalued: true
  id:
    name: id
    description: A unique identifier for a thing
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    slot_uri: schema:identifier
    identifier: true
    owner: CellularSystem
    domain_of:
    - NamedThing
    - Reference
    - BiolinkEntity
    range: uriorcurie
    required: true
  name:
    name: name
    description: A human-readable name for a thing
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    slot_uri: schema:name
    owner: CellularSystem
    domain_of:
    - NamedThing
    - BiolinkEntity
    range: string
  description:
    name: description
    description: A human-readable description for a thing
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    slot_uri: schema:description
    owner: CellularSystem
    domain_of:
    - NamedThing
    - BiolinkEntity
    range: string
  type:
    name: type
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    designates_type: true
    owner: CellularSystem
    domain_of:
    - NamedThing
    range: string