Class: DoseResponseSimilarity

Comparison of dose-response relationships between model and biological systems.

classDiagram class DoseResponseSimilarity click DoseResponseSimilarity href "../DoseResponseSimilarity/" DoseResponseSimilarity : compound_tested DoseResponseSimilarity : correlation_coefficient DoseResponseSimilarity : ec50_ratio DoseResponseSimilarity : max_response_ratio

Slots

Name	Cardinality and Range	Description	Inheritance
correlation_coefficient	0..1 Float	Correlation coefficient between dose-response curves	direct
ec50_ratio	0..1 Float	Ratio of EC50 values between model and biological system	direct
max_response_ratio	0..1 Float	Ratio of maximum responses between systems	direct
compound_tested	0..1 String	Name of compound used in dose-response testing	direct

Usages

used by	used in	type	used
FunctionalParity	dose_response_similarity	range	DoseResponseSimilarity

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/monarch-initiative/namo

Mappings

Mapping Type	Mapped Value
self	namo:DoseResponseSimilarity
native	namo:DoseResponseSimilarity

LinkML Source

Direct

name: DoseResponseSimilarity
description: Comparison of dose-response relationships between model and biological
  systems.
from_schema: https://w3id.org/monarch-initiative/namo
attributes:
  correlation_coefficient:
    name: correlation_coefficient
    description: Correlation coefficient between dose-response curves.
    from_schema: https://w3id.org/monarch-initiative/namo
    domain_of:
    - MolecularSimilarity
    - DoseResponseSimilarity
    range: float
  ec50_ratio:
    name: ec50_ratio
    description: Ratio of EC50 values between model and biological system.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DoseResponseSimilarity
    range: float
  max_response_ratio:
    name: max_response_ratio
    description: Ratio of maximum responses between systems.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DoseResponseSimilarity
    range: float
  compound_tested:
    name: compound_tested
    description: Name of compound used in dose-response testing.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DoseResponseSimilarity

Induced

name: DoseResponseSimilarity
description: Comparison of dose-response relationships between model and biological
  systems.
from_schema: https://w3id.org/monarch-initiative/namo
attributes:
  correlation_coefficient:
    name: correlation_coefficient
    description: Correlation coefficient between dose-response curves.
    from_schema: https://w3id.org/monarch-initiative/namo
    alias: correlation_coefficient
    owner: DoseResponseSimilarity
    domain_of:
    - MolecularSimilarity
    - DoseResponseSimilarity
    range: float
  ec50_ratio:
    name: ec50_ratio
    description: Ratio of EC50 values between model and biological system.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: ec50_ratio
    owner: DoseResponseSimilarity
    domain_of:
    - DoseResponseSimilarity
    range: float
  max_response_ratio:
    name: max_response_ratio
    description: Ratio of maximum responses between systems.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: max_response_ratio
    owner: DoseResponseSimilarity
    domain_of:
    - DoseResponseSimilarity
    range: float
  compound_tested:
    name: compound_tested
    description: Name of compound used in dose-response testing.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: compound_tested
    owner: DoseResponseSimilarity
    domain_of:
    - DoseResponseSimilarity
    range: string