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Class: DrugProperties

Physicochemical and pharmacological properties of a drug in PBPK models.

URI: [namo:DrugProperties](https://w3id.org/monarch-initiative/namo/DrugProperties)
classDiagram class DrugProperties click DrugProperties href "../DrugProperties/" DrugProperties : clearance DrugProperties : logp DrugProperties : molecular_weight DrugProperties : pka DrugProperties : protein_binding
## Slots | Name | Cardinality and Range | Description | Inheritance | | --- | --- | --- | --- | | [molecular_weight](molecular_weight.md) | 0..1
[Float](Float.md) | Molecular weight (g/mol) | direct | | [logp](logp.md) | 0..1
[Float](Float.md) | Lipophilicity (log P) | direct | | [pka](pka.md) | 0..1
[Float](Float.md) | Acid dissociation constant | direct | | [protein_binding](protein_binding.md) | 0..1
[Float](Float.md) | Fraction bound to plasma proteins (0 | direct | | [clearance](clearance.md) | 0..1
[Float](Float.md) | Total body clearance (L/h) | direct | ## Usages | used by | used in | type | used | | --- | --- | --- | --- | | [PBPKModel](PBPKModel.md) | [drug_properties](drug_properties.md) | range | [DrugProperties](DrugProperties.md) | ## Identifier and Mapping Information ### Schema Source * from schema: https://w3id.org/monarch-initiative/namo ## Mappings | Mapping Type | Mapped Value | | --- | --- | | self | namo:DrugProperties | | native | namo:DrugProperties | ## LinkML Source ### Direct 
name: DrugProperties
description: Physicochemical and pharmacological properties of a drug in PBPK models.
from_schema: https://w3id.org/monarch-initiative/namo
attributes:
  molecular_weight:
    name: molecular_weight
    description: Molecular weight (g/mol)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DrugProperties
    range: float
  logp:
    name: logp
    description: Lipophilicity (log P)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DrugProperties
    range: float
  pka:
    name: pka
    description: Acid dissociation constant
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DrugProperties
    range: float
  protein_binding:
    name: protein_binding
    description: Fraction bound to plasma proteins (0.0-1.0)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DrugProperties
    range: float
  clearance:
    name: clearance
    description: Total body clearance (L/h)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - DrugProperties
    range: float
### Induced 
name: DrugProperties
description: Physicochemical and pharmacological properties of a drug in PBPK models.
from_schema: https://w3id.org/monarch-initiative/namo
attributes:
  molecular_weight:
    name: molecular_weight
    description: Molecular weight (g/mol)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: DrugProperties
    domain_of:
    - DrugProperties
    range: float
  logp:
    name: logp
    description: Lipophilicity (log P)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: DrugProperties
    domain_of:
    - DrugProperties
    range: float
  pka:
    name: pka
    description: Acid dissociation constant
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: DrugProperties
    domain_of:
    - DrugProperties
    range: float
  protein_binding:
    name: protein_binding
    description: Fraction bound to plasma proteins (0.0-1.0)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: DrugProperties
    domain_of:
    - DrugProperties
    range: float
  clearance:
    name: clearance
    description: Total body clearance (L/h)
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    owner: DrugProperties
    domain_of:
    - DrugProperties
    range: float