Class: FunctionalParity

Evaluation of functional capabilities and physiological responses between systems.

classDiagram class FunctionalParity click FunctionalParity href "../FunctionalParity/" NamedThing <|-- FunctionalParity click NamedThing href "../NamedThing/" FunctionalParity : conserved_functions FunctionalParity : description FunctionalParity : dose_response_similarity FunctionalParity --> "0..1" DoseResponseSimilarity : dose_response_similarity click DoseResponseSimilarity href "../DoseResponseSimilarity/" FunctionalParity : functional_assays FunctionalParity --> "*" FunctionalAssay : functional_assays click FunctionalAssay href "../FunctionalAssay/" FunctionalParity : functional_similarity_score FunctionalParity : id FunctionalParity : impaired_functions FunctionalParity : name FunctionalParity : type

Inheritance

NamedThing
- FunctionalParity

Slots

Name	Cardinality and Range	Description	Inheritance
functional_similarity_score	0..1 Float	Quantitative score (0	direct
conserved_functions	* String	List of biological functions conserved between model and biological system	direct
impaired_functions	* String	List of functions that are impaired or absent in the model system	direct
functional_assays	* FunctionalAssay	List of functional assays used to assess parity	direct
dose_response_similarity	0..1 DoseResponseSimilarity	Comparison of dose-response relationships for therapeutic compounds	direct
id	1 Uriorcurie	A unique identifier for a thing	NamedThing
name	0..1 String	A human-readable name for a thing	NamedThing
description	0..1 String	A human-readable description for a thing	NamedThing
type	0..1 String		NamedThing

Usages

used by	used in	type	used
StructuredConcordanceResult	functional_parity	range	FunctionalParity

Identifier and Mapping Information

Schema Source

from schema: https://w3id.org/monarch-initiative/namo

Mappings

Mapping Type	Mapped Value
self	namo:FunctionalParity
native	namo:FunctionalParity

LinkML Source

Direct

name: FunctionalParity
description: Evaluation of functional capabilities and physiological responses between
  systems.
from_schema: https://w3id.org/monarch-initiative/namo
is_a: NamedThing
attributes:
  functional_similarity_score:
    name: functional_similarity_score
    description: Quantitative score (0.0-1.0) representing functional similarity.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - FunctionalParity
    range: float
  conserved_functions:
    name: conserved_functions
    description: List of biological functions conserved between model and biological
      system.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - FunctionalParity
    multivalued: true
  impaired_functions:
    name: impaired_functions
    description: List of functions that are impaired or absent in the model system.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - FunctionalParity
    multivalued: true
  functional_assays:
    name: functional_assays
    description: List of functional assays used to assess parity.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - FunctionalParity
    range: FunctionalAssay
    multivalued: true
    inlined: true
    inlined_as_list: true
  dose_response_similarity:
    name: dose_response_similarity
    description: Comparison of dose-response relationships for therapeutic compounds.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    domain_of:
    - FunctionalParity
    range: DoseResponseSimilarity
    inlined: true

Induced

name: FunctionalParity
description: Evaluation of functional capabilities and physiological responses between
  systems.
from_schema: https://w3id.org/monarch-initiative/namo
is_a: NamedThing
attributes:
  functional_similarity_score:
    name: functional_similarity_score
    description: Quantitative score (0.0-1.0) representing functional similarity.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: functional_similarity_score
    owner: FunctionalParity
    domain_of:
    - FunctionalParity
    range: float
  conserved_functions:
    name: conserved_functions
    description: List of biological functions conserved between model and biological
      system.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: conserved_functions
    owner: FunctionalParity
    domain_of:
    - FunctionalParity
    range: string
    multivalued: true
  impaired_functions:
    name: impaired_functions
    description: List of functions that are impaired or absent in the model system.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: impaired_functions
    owner: FunctionalParity
    domain_of:
    - FunctionalParity
    range: string
    multivalued: true
  functional_assays:
    name: functional_assays
    description: List of functional assays used to assess parity.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: functional_assays
    owner: FunctionalParity
    domain_of:
    - FunctionalParity
    range: FunctionalAssay
    multivalued: true
    inlined: true
    inlined_as_list: true
  dose_response_similarity:
    name: dose_response_similarity
    description: Comparison of dose-response relationships for therapeutic compounds.
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    alias: dose_response_similarity
    owner: FunctionalParity
    domain_of:
    - FunctionalParity
    range: DoseResponseSimilarity
    inlined: true
  id:
    name: id
    description: A unique identifier for a thing
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    slot_uri: schema:identifier
    identifier: true
    alias: id
    owner: FunctionalParity
    domain_of:
    - NamedThing
    - Reference
    range: uriorcurie
    required: true
  name:
    name: name
    description: A human-readable name for a thing
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    slot_uri: schema:name
    alias: name
    owner: FunctionalParity
    domain_of:
    - NamedThing
    range: string
  description:
    name: description
    description: A human-readable description for a thing
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    slot_uri: schema:description
    alias: description
    owner: FunctionalParity
    domain_of:
    - NamedThing
    range: string
  type:
    name: type
    from_schema: https://w3id.org/monarch-initiative/namo
    rank: 1000
    designates_type: true
    alias: type
    owner: FunctionalParity
    domain_of:
    - NamedThing
    range: string