Class: ExperimentalMetricToChemicalRelationship

A triple where the subject is an experimental metric, the object is a chemical, drug, or other substance, and the predicate describes the relationship between the metric and the chemical, usually MEASURED_IN_RESPONSE_TO.

URI: alzrd:ExperimentalMetricToChemicalRelationship

erDiagram ExperimentalMetricToChemicalRelationship { string direct_or_indirect string association } NamedEntity { string id string label } Chemical { string id string label } MetricOrIndicator { string id string label } ExperimentalMetricToChemicalRelationship ||--|o MetricOrIndicator : "metric" ExperimentalMetricToChemicalRelationship ||--|o Chemical : "chemical" ExperimentalMetricToChemicalRelationship ||--|o NamedEntity : "predicate" ExperimentalMetricToChemicalRelationship ||--|o NamedEntity : "metric_qualifier" ExperimentalMetricToChemicalRelationship ||--|o NamedEntity : "chemical_qualifier"

Inheritance

CompoundExpression
- ExperimentalMetricToChemicalRelationship

Slots

Name	Cardinality and Range	Description	Inheritance
metric	0..1 MetricOrIndicator	The name of an experimental metric, sign, symptom, or outcome used to measure...	direct
chemical	0..1 Chemical	The name of a chemical, drug, or other substance	direct
predicate	0..1 NamedEntity	The relationship type, generally MEASURED_IN_RESPONSE_TO to indicate a metric...	direct
metric_qualifier	0..1 NamedEntity	An optional qualifier or modifier for the experimental metric, as described i...	direct
chemical_qualifier	0..1 NamedEntity	An optional qualifier or modifier for the chemical, drug, or other substance,...	direct
direct_or_indirect	0..1 String	Whether the relationship between the metric and the chemical is direct or ind...	direct
association	0..1 String	The type of any observed association between the value of the metric and the ...	direct

Usages

used by	used in	type	used
Document	experimental_metric_to_chemical_relationships	range	ExperimentalMetricToChemicalRelationship

Identifier and Mapping Information

Schema Source

from schema: http://w3id.org/ontogpt/alzrd

Mappings

Mapping Type	Mapped Value
self	alzrd:ExperimentalMetricToChemicalRelationship
native	alzrd:ExperimentalMetricToChemicalRelationship

LinkML Source

Direct

name: ExperimentalMetricToChemicalRelationship
description: A triple where the subject is an experimental metric, the object is a
  chemical, drug, or other substance, and the predicate describes the relationship
  between the metric and the chemical, usually MEASURED_IN_RESPONSE_TO.
from_schema: http://w3id.org/ontogpt/alzrd
is_a: CompoundExpression
attributes:
  metric:
    name: metric
    description: The name of an experimental metric, sign, symptom, or outcome used
      to measure the effects of treatments on symptoms or diagnostics, or of the progression
      of Alzheimer's disease and related dementias. In experimental animal models
      these are analogues of cognitive impairment or indicators of disease progression
      modeling those observed in humans. Examples are Amyloid beta (Aβ) levels, Morris
      water maze test, tau phosphorylation, neurofibrillary tangles, and cognitive
      decline.
    from_schema: http://w3id.org/ontogpt/alzrd
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: MetricOrIndicator
  chemical:
    name: chemical
    description: The name of a chemical, drug, or other substance. Examples are "donepezil",
      "Aβ42", "Aβ40", "tau", "insulin", "caffeine", "nicotine", "alcohol".
    from_schema: http://w3id.org/ontogpt/alzrd
    domain_of:
    - Document
    - ExperimentalMetricToChemicalRelationship
    range: Chemical
  predicate:
    name: predicate
    description: The relationship type, generally MEASURED_IN_RESPONSE_TO to indicate
      a metric is measured in response to a chemical.
    from_schema: http://w3id.org/ontogpt/alzrd
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    - Triple
    range: NamedEntity
  metric_qualifier:
    name: metric_qualifier
    description: An optional qualifier or modifier for the experimental metric, as
      described in the input text. This may include the method of measurement or the
      specific assay used.
    from_schema: http://w3id.org/ontogpt/alzrd
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: NamedEntity
  chemical_qualifier:
    name: chemical_qualifier
    description: An optional qualifier or modifier for the chemical, drug, or other
      substance, as described in the input text. This may include the dose or route
      of administration.
    from_schema: http://w3id.org/ontogpt/alzrd
    rank: 1000
    domain_of:
    - ExperimentalMetricToChemicalRelationship
    range: NamedEntity
  direct_or_indirect:
    name: direct_or_indirect
    description: Whether the relationship between the metric and the chemical is direct
      or indirect. UNKNOWN if this is not specified in the text or is unclear.
    from_schema: http://w3id.org/ontogpt/alzrd
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: string
  association:
    name: association
    description: The type of any observed association between the value of the metric
      and the chemical. May be "positive", "negative", "inconclusive", or UNKNOWN
      if this is not specified in the text or is unclear.
    from_schema: http://w3id.org/ontogpt/alzrd
    domain_of:
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: string

Induced

name: ExperimentalMetricToChemicalRelationship
description: A triple where the subject is an experimental metric, the object is a
  chemical, drug, or other substance, and the predicate describes the relationship
  between the metric and the chemical, usually MEASURED_IN_RESPONSE_TO.
from_schema: http://w3id.org/ontogpt/alzrd
is_a: CompoundExpression
attributes:
  metric:
    name: metric
    description: The name of an experimental metric, sign, symptom, or outcome used
      to measure the effects of treatments on symptoms or diagnostics, or of the progression
      of Alzheimer's disease and related dementias. In experimental animal models
      these are analogues of cognitive impairment or indicators of disease progression
      modeling those observed in humans. Examples are Amyloid beta (Aβ) levels, Morris
      water maze test, tau phosphorylation, neurofibrillary tangles, and cognitive
      decline.
    from_schema: http://w3id.org/ontogpt/alzrd
    alias: metric
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: MetricOrIndicator
  chemical:
    name: chemical
    description: The name of a chemical, drug, or other substance. Examples are "donepezil",
      "Aβ42", "Aβ40", "tau", "insulin", "caffeine", "nicotine", "alcohol".
    from_schema: http://w3id.org/ontogpt/alzrd
    alias: chemical
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - Document
    - ExperimentalMetricToChemicalRelationship
    range: Chemical
  predicate:
    name: predicate
    description: The relationship type, generally MEASURED_IN_RESPONSE_TO to indicate
      a metric is measured in response to a chemical.
    from_schema: http://w3id.org/ontogpt/alzrd
    alias: predicate
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    - Triple
    range: NamedEntity
  metric_qualifier:
    name: metric_qualifier
    description: An optional qualifier or modifier for the experimental metric, as
      described in the input text. This may include the method of measurement or the
      specific assay used.
    from_schema: http://w3id.org/ontogpt/alzrd
    alias: metric_qualifier
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: NamedEntity
  chemical_qualifier:
    name: chemical_qualifier
    description: An optional qualifier or modifier for the chemical, drug, or other
      substance, as described in the input text. This may include the dose or route
      of administration.
    from_schema: http://w3id.org/ontogpt/alzrd
    rank: 1000
    alias: chemical_qualifier
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - ExperimentalMetricToChemicalRelationship
    range: NamedEntity
  direct_or_indirect:
    name: direct_or_indirect
    description: Whether the relationship between the metric and the chemical is direct
      or indirect. UNKNOWN if this is not specified in the text or is unclear.
    from_schema: http://w3id.org/ontogpt/alzrd
    alias: direct_or_indirect
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - ExperimentalMetricToTaxonRelationship
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: string
  association:
    name: association
    description: The type of any observed association between the value of the metric
      and the chemical. May be "positive", "negative", "inconclusive", or UNKNOWN
      if this is not specified in the text or is unclear.
    from_schema: http://w3id.org/ontogpt/alzrd
    alias: association
    owner: ExperimentalMetricToChemicalRelationship
    domain_of:
    - ExperimentalMetricToDiseaseRelationship
    - ExperimentalMetricToEnvironmentRelationship
    - ExperimentalMetricToChemicalRelationship
    range: string